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5-Hole Box
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- "5-choice serial reaction time" task for mice or rats
- Food or liquid reinforcement using automatic pellet feeders or ultra-precise microliter liquid
dispensers
- Variable reinforcer position (rear or front wall)
- Present bursts of white noise as distractor (selective attention)
- Optional sine sound presentation (2…20kHz)
- Integrated flexible program editor for user-defined protocols
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The TSE 5-Hole-Box system is designed to perform attention tests based on visual discrimination
("5-choice serial reaction time") in which short-lasting visual stimuli are given in pseudo-random
order in all of 5 stimulus holes or in selected holes only. Responses into the correct holes are
reinforced. Reward can be given directly into the response holes or in the start hole on the opposite
wall. Measures of performance include response latencies, premature responses and number of
nose-pokes. For maximum flexibility use the integrated program editor for generation of user-defined
paradigms!
Dustless precision pellets for all applications are available from TSE.
Operant Behavior Systems
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- Versatile modular Skinner boxes for rats and mice
- Standard, weight-adjustable, illuminated or retractable levers or nose-poke response modules
- Intravenous self-administration of drugs with microliter liquid dispensers for volumes as small
as 0.5 µl
- Self-stimulation with intracranial electrodes
- Standard schedules include FR, VR, PR, FI, VI, PI, DRH and DRL, Geller conflict, drug discrimination
- Integrated flexible program editor for user-defined protocols
- Cumulative recorder graphs and test-specific results tables
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Our fully computerized Skinner boxes are custom-built from a wide choice of individual components. We
provide a variety of different function modules that are easily mounted into the base construction. Each
Skinner box is a completely self-contained unit in a sound and light-attenuating fan-ventilated housing
suited for all standard operant tasks.
Box control and data acquisition are made easy with our comprehensive software package. All Skinner
boxes can run one of the preprogrammed schedules that are continuously being further developed according
to the latest research applications. Alternatively individually designed schedules can be created
employing our unique easy-to-learn free programming language.
Special box configurations allow Learned Helplessness experiments to
be performed.
Place Preference System
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- Fully automated three-compartment test boxes for mice or rats
- Select from a variety of wall colors and floor inserts to facilitate discrimination between
compartments
- Closed dividers, tunnel gates, manual or software-controlled doors
- High-resolution infrared sensors are used to monitor entries into compartments and locomotor
activity
- Up to 8 boxes can be operated simultaneously with one PC
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Conditioned place preference is a widely used technique to assess the rewarding properties of a
psychotropic drug. Treatment with a specific preparation is repeatedly paired with a distinct
environment while a control treatment is paired with a different environment. When the animal has
access to both environments, preference for the drug-paired cues will indicate the rewarding effects of
the test drug.
Our test boxes are available in a variety of configurations with easily exchangeable wall elements,
integrated lamps used to counterbalance preferences for specific compartments, and differently
structured floor inserts to facilitate tactile discrimination. Data acquisition is started automatically
when the first light-beam sensor is interrupted after the animal has been placed in the box. Data
analysis includes number of visits, time spent and distance traveled in each compartment.
Fear Conditioning System
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Designed to examine the retention of shock induced fear the system provides all components necessary
to investigate into anxiolytic drugs. Trainings, tests and the subsequent analysis are easily
performed. The experimental modules can be adapted to your requirements. All features are straight
forward in use. |
Passive Avoidance
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Designed for the classical "step-through" paradigm this test box features a lit and a dark
compartment divided by a special manually operated or motorized door insert. The floor grid is
delivers an electric shock when the animal transfers into the dark compartment. Infrared sensors
allow continuous monitoring of animal location. All components are controlled via PC-compatible
software which also analyses the response latency.
We also provide economical "step-down" passive avoidance test systems for rats and mice. |
Active Avoidance (Shuttle-Box)
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- Fully computerized bi-directional avoidance conditioning system
- Software-controlled light & shock application
- Software-controlled stimulus sound (10 kHz fixed or adjustable between 2…20 kHz)
- Application of WAV files for acoustic discrimination
- Optional flexible program editor for generation of user-defined trial procedures
- Can be converted into a Passive Avoidance box with the optional
Passive Avoidance conversion set
Our Active Avoidance setup allows simultaneous operation of up to 4 rectangular two-compartment boxes.
We provide gates, tunnels, doors, holes or hurdles with optional electrical stimulus that can be easily
exchanged. Monitoring of animal movement and location is performed with uni-dimensional infrared sensor
strips with species-specific sensor distances (28mm or 14mm).
The easy-to-use Windows software is designed to run a variety of test protocols. Adjustable time
parameters include habituation, time to shock, shock length, maximum run duration and interstimulus
interval. Data analysis provides a results table listing conditioned, unconditioned and interstimulus
transfers and mean reaction times. Measuring values of several animals can be summarized for group
analysis. |
Pole Jump System (Active Avoidance)
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- One-way active avoidance task for rats and mice
- Automated software-controlled generation of conditioned and unconditioned stimuli
- The pole is fixed to the box ceiling and has a structured surface that provides a grip for the
animal
- Microswitch sensors register the animal's presence on the pole
- Multi-purpose programming software for user-defined test protocols
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The pole-jump avoidance task is a discriminated one-way active avoidance task. Our fully automated test
boxes for mice and rats are equipped with shockable grid floor, house / stimulus light and loudspeaker.
The acrylic front door allows the operator to observe the animal throughout the experiment. The animal
has to climb up a pole in response to a stimulus - usually a sound - to avoid a shock delivered through
the floor of the box. User-defined experimental designs for data acquisition and test trials can be
created using a flexible programming software.
Dustless Precision Pellets
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Our nutritionally balanced dustless precision pellets are
suited for all applications where highly precise feeding is required.
- The pellets are nutrionally balanced and virtually dust-free.
- Hassle-free performance in automatic feeders.
- Suitable as a maintenance diet as well as a behavioral reward.
- Available in sizes of 14/ 20/ 45 mg.
- Tested routinely for hardness, weight and height.
- Produced in a GMP environment assuring accurate and consistent diet composition.
Certification
The nutritional content on every lot of diet is analyzed by an independent laboratory prior to
shipment. The results of analysis are available upon request.
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Nutritional Assays
Nutritional assays and chemical screens are provided to ensure product consistency.
Ingredients
Protein, fat, fiber, ash and moisture
Purified Formula
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Caloric Value
3.62 cal/mg
Ingredients
Casein, sucrose, fiber, dextrose, Dl-methionine, L-cystine, choline bitartrate, corn oil, corn syrup,
mineral mix, vitamin mix, flowing and flavoring agents
Shelf Life
12 months in cool, dry storage
Ordering Information
| Cat-No. | Description |
| 259901-PEL-14/50T |
Precision-Pellets 14 mg, dustless
BioServ Purified Formula
For TSE Pellet Dispenser (14 mg) and other pellet dispensers.
Pack = 50.000 pellets. |
| 259901-PEL-20/50T |
Precision-Pellets 20 mg, dustless
BioServ Purified Formula
For TSE Pellet Dispenser (20 mg) and other pellet dispensers.
Pack = 50.000 pellets. |
| 259901-PEL-45/50T |
Precision-Pellets 45 mg, dustless
BioServ Purified Formula
For TSE Pellet Dispenser (45 mg) and other pellet dispensers.
Pack = 50.000 pellets |
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Copyright © 1995 - 2008 TSE Systems International Group - All rights reserved.
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