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Automated Isolated Organ Bath Systems
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With our automated systems for research on isolated organ preparations you have the flexibility and
versatility you've always wanted in your lab! Due to their modular design they can be built
according to your specification.
- Proven hardware components designed for long term use contribute to the perfect system
design
- The computerized control of motors, valves and pumps and the automated data acquisition and
analysis of the measuring signals make these systems perfectly suited for any application
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Basic Isolated Organ Bath
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These small manually-operated testing systems are ideal for the student laboratory to study smooth
muscle preparations. Due to their compact design minimum bench space is required.
- They can be configured as 1-place or dual-place units and come complete with isotonic or
isometric transducers measuring range as required), jacketed organ bath, warming coil for
perfusate, organ glass hook with integrated aeration frit, fluid reservoir and pumping unit
- The Universal Transducer Amplifier is ready for connection to a chart
recorder or computer
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Langendorff / Working Heart Systems
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Isolated perfused heart studies are a proven and valuable tool in assessing cardiac chronotropic
(effect on heart rate), ionotropic (contractile strength) and vascular drug effects.
Due to their flexible modular design our systems according to Langendorff are suited for all animal
species including mice and can be operated with constant pressure and constant flow, in recirculating
and non-recirculating mode.
- They can also be configured for "Working Heart" studies
- The setup includes all transducers, glassware and accessories to measure all essential
parameters such as LVP, dpdt, systolic, diastolic and mean aortal pressure, ECG, heart rate as well
as coronary and aortal flow
- For comfortable computerized data acquisition and analysis the setup can be easily connected to
our BioSys software package
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Isometric Transducers
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Our research grade isometric transducers are designed for the precise measurement of contraction
force.
- Various load forces are available starting from 0...5g
- High linearity and an extraordinary small zero point drift make these transducers ideal suited
for measuring even very small signal changes
- They can also be operated in a horizontal position, e.g. for vessel ring preparations
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Isotonic Transducers
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Isotonic transducers measure contraction displacement in all smooth muscle preparations. They are
characterized by high linearity, accuracy and sensitivity.
- A balance control is provided to zero the output of the transducer at a convenient position
- They come complete with tissue fixing hooks, calibration ladder and counter-weights
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Universal Transducer Amplifier
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The universal transducer amplifier is a small and light-weight single-channel amplifier and signal
conditioner that accepts TSE isotonic and isometric transducers as well as TSE blood pressure
transducers. It can also be configured for other laboratory signals. With its built-in mains supply
it provides the connected transducer with electricity.
- The digital LCD display shows the signal in calibrated units
- A BNC output connector allows direct connection to a chart recorder or PC (standard output 8 V
for full rated load)
- With 3 different measuring ranges, offset control and filter selector (1, 10, 100 Hz)
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VasoTrack Vessel Analyzer
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VasoTrack is a computerized videomicroscopic system for the online analysis of pressurized blood
vessel dimensions in vitro. You can now determine changes in vessel diameter and wall thickness due
to spontaneous or drug-induced contraction or relaxation with high objectivity under physiologic
conditions!
- The fully automated data acquisition is performed in a user-friendly Windows environment
- Vessel dimensions are presented in a continuous diameter-versus-time diagram and stored in an
ASCII file for further statistical calculations
- The versatile system can be adapted to specific properties of the vessel type under
investigation by adjusting a variety of detection parameters
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