Fear Conditioning System Advanced

The TSE Fear Conditioning System is a widely used and established system for studying contextual and cued fear learning, retention and extinction in mice and rats. In classical fear conditioning, the animal associates a given cue (tone or light stimulus) with an electric shock. Alternatively for context conditioning only an electric shock can be given in the box. During a subsequent retention trial the animal is tested for its natural fear response (freezing) to the cue and/or the context.

The Fear Conditioning software allows the free definition of trace & delay fear conditioning experimental designs. The user-defined sequence of stimuli is applied in up to 8 measuring stations that are controlled by a single PC. The comprehensive graphical and numerical evaluation of the animal's fear response includes calculation of freezing frequency & duration, activity, hyperactivity & hyperactivity times, rearing events, average speed and % area explored.

• High-resolution light-beam frames for ultra-precise movement detection in 3 dimensions – up to 100Hz sampling rate
• Free definition of experimental designs
• "New Context" adjustment of visual, auditory and tactile cues
• Optional computer-control of sound and noise amplitude and sine frequency
• Can be converted into a Light-Dark or Place Preference System
• Ultra-sound loudspeakers for evaluation of panic responses in rats