Bronchospasm Measuring System

The bronchospasm measuring setup allows to easily determine changes in airway resistance of an anaesthetized animal that is artificially ventilated at a fixed pump volume. Spasmodic or spasmolytic effects of a test drug will induce variations in the so-called "respiratory overflow" that can be measured as changes in air flow rate by a sensitive electronic air flow transducer.

After filtering and amplification the flow signal is output on a chart recorder. The drug induced effect on ventilatory performance can be read off from the waveform amplitude. The system can also be connected to a data acquisition system if desired.