Spatial Learning & Memory
The Barnes Maze paradigm is a hippocampal-dependent task that is widely used for the assessment of spatial working memory and/or reference memory. The animal has to find an escape hole on a brightly lit surface by using extra-maze cues.
The TSE Barnes Mazes are used in combination with a video-tracking system such as the TSE VideoMot2 system. Barnes mazes with 122cm diameter are available with 20 (rats) or 40 (mice) holes. For mice, a small version with 96cm diameter and 20 holes is also available that is especially suited for 3-point tracking analysis. Select a white or a gray maze to achieve maximum contrast with your animal. The easily removable underframe can be folded for space-saving storage when the maze is not in use.
VideoMot2 displays the movement track thus allowing to see the search strategy of the animal at a glance (random, serial, spatial). Latency to target hole, total distance traveled and average speed, as well as visits and cumulative time of stay in quadrants, are automatically calculated. In addition, the event monitor can be used to manually protocol behaviors that cannot be detected automatically.
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