Grip Strength Meter

Muscle Strength

The TSE Grip Strength Meter is a system for determining the gripping strength of small laboratory animals (rat, mouse). Within the context of neuromuscular investigations, this test can be used to quantify the effects of hormones, toxins, muscle relaxants as well as disease or the aging process on the muscular strength of the animal.

The animal is lifted and held by its tail so that the paws can grasp a special grip mounted to a high-precision force sensor. A variety of grip types are available (rod, mesh, trapezoid); custom grips are possible. The animal is then pulled gently backward until it releases the grip – the release force is shown on the digital display of a connected control unit. The analog waveform also can be displayed on a chart recorder.

For maximum convenience, the setup can be connected to a computer. If the animal releases the grip, the peak force as well as the force at the time of release are shown in the Grip Strength Meter software. Several measurements are usually done in succession; data is stored in one common file for easy group analysis with statistics packages.

Danilov CA, Gu Y, Punj V, Wu Z, Steward O, Schönthal AH, Tahara SM, Hofman FM, Chen TC. Intravenous delivery of microRNA-133b along with Argonaute-2 enhances spinal cord recovery following cervical contusion in mice. The Spine Journal 2020; 7: 1138-51.

Hu S, Zheng J, Du Z, Wu G. Knock down of lncRNA H19 promotes axon sprouting and functional recovery after cerebral ischemic stroke. Brain Research 2020; 1732: 146681

Kalita J, Kumar V, Misra UK, Bora HK. Movement Disorder in Copper Toxicity Rat Model: Role of Inflammation and Apoptosis in the Corpus Striatum. Neurotox Res 2020; 37(4): 904–12.

Misra UK, Singh SK, Kalita J, Kumar A. Astrocyte activation following nitrous oxide exposure is related to oxidative stress and glutamate excitotoxicity. Brain Res 2020; 1730:146645

Sasani A, Hornig S, Grzybowski R, Cordts K, Hanff E, Tsikas D, Böger R, Gerloff C, Isbrandt D, Neu A, Schwedhelm E, Choe CU. Muscle phenotype of AGAT- and GAMT-deficient mice after simvastatin exposure. Amino Acids 2020; 52: 73–85.

Features

High-precision force sensor module.
Sensor capacity for mice up to 600 Newton.
Sensor capacity for rats up to 2000 Newton.
Mice grips: 2-paw (forelimbs) and 4-paw measurement.
Rat grips: Forelimb measurement ..
Stand-alone or PC-based system (USB connection)..

Application

Motor Function .

Disease models

Parkinson´s.
Stroke .