The Hole Board exploration test is a behavioral paradigm especially used in mice. The animal is placed on a floor equipped with a symmetrical arrangement of holes. Head dipping into these holes is used as a measure of exploration. The effect of stress, anxiety, or drugs targeting different neurotransmitter systems on head dipping behavior is evaluated.
The multi-purpose ActiMot2 system can be configured for Hole board experiments. A Hole Board with species-specific hole size is placed into an Open Field. With a grid of infrared sensors mounted below the board, hole visits are reliably detected using the Hole-Board plug-in of the comprehensive “ActiMot2 Advanced” software package. Gross activity on the board can be assessed by adding an additional sensor level that is located above the board. For detailed movement analysis on the board add a second 2-dimensional sensor frame and/or an optional rearing detector.
TSE Systems also provides a cost-effective stand-alone “Hole-Board-Only” software that can also be configured for a spatial version of the Hole-Board test that uses baited holes.
The Hole Board exploration test can also be configured in a Multi Conditioning setup.
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