Large selection of arenas for new context flexibility
Adjustment of visual, auditory, spatial and tactile cues
Software controlled noise and light for variation of environmental parameters inside the housing
Flexible definition of experimental designs – for contextual/cued and delay/trace fear conditioning
Programmable TTL signals to control external devices such as optogenetics laser generators
Fear Conditioning is a widely used paradigm to study associative emotional memory. An unconditional fear stimulus (foot shock) induces fear – displayed in form of freezing: the animal remains in a motionless, defensive posture. After one or several pairings of the foot shock with a neutral stimulus like a tone during training, this neutral stimulus becomes a conditional fear stimulus, which alone is then able to evoke a freezing response. This conditioned response - among others - is evaluated in the subsequent retention trial. The animal can be tested for its fear of the context and the conditioned stimulus/cue. Broadly applicable for animal models of Alzheimers, anxiety disorders and diseases with cognitive decline.