Conditioned place preference is widely used in preclinical research to assess the rewarding or aversive effects of drugs. It utilizes a specially designed 2-compartment arena. The task involves the repetitive association of one compartment (equipped with distinct contextual cues) with the effects of the drug and the association of the second compartment with the absence of drug effects. When the animal has access to both compartments during a subsequent test session, more time spent in the drug-paired compartment reflects rewarding/addictive properties of the drug, whereas less time spent in the drug-paired compartment reflects aversive properties.
The Place Preference module of the Multi Conditioning System belongs to the family of “2-compartment paradigms”, operated with a universal software package granting maximal user-friendliness and offering unsurpassed flexibility.