Depression, Behavioral Despair
The Tail Suspension Test is conceptually similar to the Porsolt swim test. When rodents are suspended by their tails, they initially show agitation and (later) immobility being kept in a stressfull position. The cumulative immobility time is a measure of the animal's degree of "helplessness". This behavior is sensitive to anti¬depressants.
The TSE Tail Suspension Monitor is equipped with sensitive force sensors (strain gauge) that pick up the animal's movements and transmits the measured values to the convenient TSE Tail Suspension software. Time of mobility, time immobile and movement amplitude can be calculated for up to 8 measuring places simultaneously (or staggered).