International Projects

At TSE Systems, it is our explicit aim to bring together industry and science in a mutually beneficial way. We are therefore honored and grateful to be included in a number of EU projects. In these projects, among them RATstream and PhenoScale, TSE Systems was chosen as an SME project partner due to its particular expertise in providing highly customized, automated modular analysis systems.

RAT stream Project (2007 - 2010)

"European project on the characterization of transgenic rat models for neurodegenerative and psychiatric diseases: Automated home cage analyses, live imaging and treatment".

Within this first European project on automated phenotyping the RATstream consortium focuses on high-throughput phenotype characterization of rats, in order to identify animal models of neurodegenerative and neuropsychiatric diseases such as Huntington's disease, Parkinson's disease or Spinocerebellar ataxia type 17. As the main technological partner within RATstream TSE Systems successfully developed the TSE PhenoMaster for rats which already lead to first scientific publications.

PhenoScale Project (2009 - 2012)

"Large-scale, high-throughput automated systems for phenotyping mouse models of human disease – PhenoScale"

TSE Systems is the official technology partner in the European Union PhenoScale Project. The goal of the PhenoScale project is to automate phenotyping in large-scale manner using standard protocols or SOPs, such as those contained in the European Mouse Phenotyping Resource of Standardized Screens (EMPReSS) with the aim of adding economies of scale, enhancing automated data capture and increasing throughput.

Objectives of the PhenoScale Project

  • Development of a new high-throughput automated phenotyping platform using home cage monitoring on the basis of the TSE PhenoMaster System
  • Development of new EMPReSS SOP's using this novel system and validation of this approach with selected mouse models at different European mouse clinics (cross-checking / cross-validation)
  • Optimization of the high-throughput technology systems by advanced interfacing and extended software capabilities

Scientific Partners