From Mechanism to Medicine: What Drugs That Reached the Clinic Have in Common — and What Held Others BackWhat 2,500+ studies reveal about the relationship between in vivo data quality and translational success – and what it means for the next generation of… Learn more
Polyagonist Therapies in Obesity: A systems-level case study enabled by continuous in vivo phenotypingIntroduction Obesity and type 2 diabetes are not single-pathway diseases. They emerge from a complex disruption of whole-body energy homeostasis involving the gut, brain, pancreas,… Learn more
Micro-Environmental Humidity and Temperature in Rodent Metabolic Researchby Pierre-Louis Ruffault, PhD Cage-level humidity and temperature in rodent metabolic research play a critical yet often underestimated role in shaping thermogenesis, energy expenditure, and… Learn more
Why Alzheimer's Mouse Models Show Cognitive Rescue That Doesn't TranslateOver 400 drugs have rescued cognition in Alzheimer’s mouse models. Fewer than 5 have shown efficacy in humans (Langness et al., 2025). That gap is… Learn more
8 Drug Classes Tested in IntelliCage: What Group-housed Cognitive Phenotyping Revealed that Standard Tests MissedIntelliCage is an automated home-cage behavioral testing system developed by TSE Systems. It enables continuous cognitive phenotyping of group-housed rodents using RFID individual identification and… Learn more
How Handling Stress Contaminates Behavioral Data and What to do InsteadThere is a confounder in almost every behavioral neuroscience study that nobody mentioned in the methods section. Handling stress. The moment you pick up an… Learn more
BonnBrain 2026We are excited to share that we will participate in BonnBrain 2026 – From Genes to Circuits and Behavior, taking place March 23–25, 2026 at… Learn more
American Physiology Summit 2025Meet us at booth #1314 in American Physiology Summit from April 24-27 in Baltimore. Held annually by the American Physiological Society (APS), the Summit convenes… Learn more
Fens Forum 2026Join TSE Systems at booth booth #98 and thousands of neuroscientists in Barcelona from 6–10 July 2026 for Europe’s premier international neuroscience meeting. By submitting your abstract,… Learn more