Pioneered by TSE, our Advanced Gas Sensors detect H₂ (hydrogen), CH₄ (methane), and H₂S (hydrogen sulfide) in rodents for Gnotobiotic Research, including Germ-free Animals.
H2 evolution reflects adaptation to dietary carbohydrates
Mice fed with a low digestible diet produced more hydrogen than their counterparts, while at ad libitum consumption of a high digestible diet, hydrogen levels were left unchanged.
Gnotobiotic and germ-free animals require specialized housing to maintain their unique microbiological status and protect both the animals and the laboratory environment. Our customized PhenoMaster Isolators and Iso-Cages address this need perfectly.
By adding any of these special enclosures, you can confidently conduct research with gnotobiotic mice while keeping both your animals and the lab environment safe.
Fecal collection is vital for microbiome analysis. This non-invasive and simple procedure provides a treasure trove of information about the diverse microorganisms inhabiting the digestive tract, offering crucial insights into gut health and its role in metabolic modulation. To ensure optimal sample preservation, we also offer an automated for immediate sample freezing after collection. This minimizes degradation and guarantees the integrity of your samples for further analysis.
This metabolic cage can be equipped with sensors for monitoring of food and water intake. Furthermore, it prioritizes animal welfare with a special resting plate on the grid floor. This not only reduces stress for animals, but also minimizes potential data skewing caused by stress factor, ensuring the validity of your research.
Fernández-Calleja, J. M. S., Bouwman, L. M. S., Swarts, H. J. M., Billecke, N., Oosting, A., Keijer, J., & van Schothorst, E. M. (2019).. Nutrients, 11(9), Article 9
Hoces, D., Lan, J., Sun, W., Geiser, T., Stäubli, M. L., Barazzone, E. C., Arnoldini, M., Challa, T. D., Klug, M., Kellenberger, A., Nowok, S., Faccin, E., Macpherson, A. J., Stecher, B., Sunagawa, S., Zenobi, R., Hardt, W.-D., Wolfrum, C., & Slack, E. (2022).. PLOS Biology, 20(9), e3001743
Fernández-Calleja, J. M. S., Konstanti, P., Swarts, H. J. M., Bouwman, L. M. S., Garcia-Campayo, V., Billecke, N., Oosting, A., Smidt, H., Keijer, J., & van Schothorst, E. M. (2018).. Scientific Reports, 8(1), Article 1.