Microbiome Activity Monitoring

Pioneered by TSE, our Advanced Gas Sensors detect H₂ (hydrogen), CH₄ (methane), and H₂S (hydrogen sulfide) in rodents for Gnotobiotic Research, including Germ-free Animals.

Gain Comprehensive Insights on Microbiome Dynamics

PhenoMaster leads in sensor innovation, enabling real-time monitoring of microbiome activity in lab animals and elevating research precision. This advancement is vital for scientists investigating germ-free animals in metabolic, microbiome, and aging studies. Paired with critical modules like food intake monitoring and control, feces collection, and indirect calorimetry, researchers gain profound insights into the impact of diet or treatments on microbiome dynamics.

H2 evolution reflects adaptation to dietary carbohydrates

Mice fed with a low digestible diet produced more hydrogen than their counterparts, while at ad libitum consumption of a high digestible diet, hydrogen levels were left unchanged.

Microbiome activity monitoring

Ensuring Safety for Gnotobiotic and Germ-Free Rodent Research

Gnotobiotic and germ-free animals require specialized housing to maintain their unique microbiological status and protect both the animals and the laboratory environment. Our customized PhenoMaster Isolators and Iso-Cages address this need perfectly.

By adding any of these special enclosures, you can confidently conduct research with gnotobiotic mice while keeping both your animals and the lab environment safe.

Microbiome activity monitoring

Metabolic PhenoCage for Urine and Fecal Sample Collection

Fecal collection is vital for microbiome analysis. This non-invasive and simple procedure provides a treasure trove of information about the diverse microorganisms inhabiting the digestive tract, offering crucial insights into gut health and its role in metabolic modulation. To ensure optimal sample preservation, we also offer an automated for immediate sample freezing after collection. This minimizes degradation and guarantees the integrity of your samples for further analysis.

This metabolic cage can be equipped with sensors for monitoring of food and water intake. Furthermore, it prioritizes animal welfare with a special resting plate on the grid floor. This not only reduces stress for animals, but also minimizes potential data skewing caused by stress factor, ensuring the validity of your research.


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