Multi Conditioning System

Multi-Purpose Platform for Ten Behavioral Paradigms

Multi Conditioning system

First Modular Behavioral Test Platform

The Multiconditoning System (MCS) empowers researchers by enabling comprehensive behavioral testing (learning, memory, emotion, anxiety) within a single, automated platform. MCS consolidates workflows, eliminating the need for multiple setups and saving valuable bench space. Generate reproducible results with confidence.

MCS offers unmatched versatility for diverse research needs. Removable floors and interchangeable test arenas adapt to a wide range of behavioral assays. Additionally, the powerful software, with 3 comprehensive packages allows running and analysis of over 10 behavioral tests.

Experience the benefits of MCS research: reduced costs, minimized space requirements, enhanced data accuracy, and superior reproducibility.

Available Modules

Fear Conditioning

Open Field and Activity

Active & Passive Avoidance

Place Preference

Light-Dark Test

Learned Helplessness

Latent Inhibition

Panic Response

Hole-Board Exploration

Transform Your Lab: Consolidate with 10-in-1 Research Power

Simplify Your Workflows: MCS eliminates the need for multiple standalone systems. Conduct a range of neurofunctional tests – from basic behavior to complex cognitive assessments – all within a single, versatile platform.

Early-Stage Efficiency: Identify promising drugs faster with MCS’s rigorous testing capabilities under controlled conditions. Gain valuable insights for in-depth analysis.

Clever Design, Big Savings: MCS aligns with GLP standards, saving you valuable bench space and resources.

Embrace efficiency and consolidate your research with the power of MCS.

Innovate Your Experience with

High resolution 3D movement detection

Parallel video monitoring from up to 2 angles

Sound & light controlled environment

Up to 4 units operated by a single PC

Testing under any lighting condition

User-friendly software including basic GLP features

Explore Diverse Testing Arenas

Discover an Array of Testing Arenas, Tailored for Mouse and Rat Sizes. Choose from a Spectrum of Colors and Subjects for Personalization. Explore Further Options in Our Knowledge Center ‘Arena Selection List’.

Fear Conditioning Arena

Place Preference Arena

Passive Avoidance Arena

Active Avoidance Arena

Open Field Arenas

“The first advantage we observed in using the MCS platform is the capacity to perform behavioral testing in an insulated and ventilated “closed” container, that offers full control over external conditions. The second advantage in using the MCS is the immense variety of control parameters, so that we can tailor each protocol in detail, providing both accuracy and experimental precision for protocol validation. ”

Nikolas Dietis
Assistant Professor of Pharmacology at the Medical School | University of Cyprus

“Finally, forward translation in neuropsychopharmacology: With our mouse model of stress-induced excessive aversion processing – for which the MCS is essential – we are able to identify novel mechanisms-of-action that are efficacious in patients with major neuropsychiatric disorders.”

Christopher Pryce, PhD
Professor, Neurobiology and Biological Psychiatry | Psychiatric University Hospital Zurich and University of Zurich

Trusted by

Publications

Keller C, Rading S, Bindila, L, Karsak M Behavioral Studies of p62 KO Animals with Implications of a Modulated Function of the Endocannabinoid System Cells 2022; 11: 1517

Ineichen C, Greter A, Baer M, Sigrist H, Sautter E, Sych Y, Helmchen F, Pryce CR. Basomedial amygdala activity in mice reflects specific and general aversion uncontrollability. Eur J Neurosci (2020); Dec 18. Online ahead of print

Khalaf O, Gräff J. Reactivation of recall-induced neurons in the infralimbic cortex and the basolateral amygdala after remote fear memory attenuation. Front Mol Neurosci 2019; 12: 70

Richetto J, Polesel M, Weber-Stadlbauer U. Effects of light and dark phase testing on the investigation of behavioural paradigms in mice: relevance for behavioural neuroscience. Pharmacol Biochem Behav 2019; 178: 19-29.

Wang G, Xie H, Wang L, Luo W, Wang Y, Jiang J, Xiao C, Xing F, Guan JS. Switching from fear to no fear by different neural ensembles in mouse retrosplenial cortex. Cereb Cortex 2019; 29(12): 5085-97.

Paul AK, Gueven N, Dietis N. Age-dependent antinociception and behavioral inhibition by morphine. Pharmacol Biochem Behav 2018;168: 8-16.

Luo W, Yun D, Hu Y, Tian M, Yang J, Xu Y, Tang Y, Zhan Y, Xie H, Guan JS Acquiring new memories in neocortex of hippocampal-lesioned mice Nat Commun 2022; 13(1): 1601

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Center of Knowledge