Measuring Exercise: Running & Lifting

Advanced Running Wheels for Deeper Behavioral Analysis

Discover the versatility of our PhenoMaster system, offering classic voluntary running wheels and a spectrum of options tailored to diverse research needs. Alongside the classic, we offer innovative solutions like the workload wheel, complex wheel, and exclusive stand-alone calorimetric wheel for cardio-metabolic research. Providing researchers with unparalleled flexibility, our system accommodates varied experimental requirements effortlessly. With a slim design, ample space, and intuitive maintenance features, our comprehensive running wheel solutions seamlessly elevate your research endeavors.

Diverse Functionalities

Time- and distance-controlled running with enable / disable function

UNIQUE programmed progressive resistance running routines

Paired running: running profile of experimental animal is imposed onto a control animal

Motor skill evaluation wheel: variable distance between cross bars by removing selected rungs for detection of motor skill deficits and motor skill learning – UNIQUE

Motivated running: running for food/liquid in combination with the food/liquid access control unit

UNIQUE Combination with the operant wall for complex learning tasks: running as a reward

Stand-Alone Calo Wheel for Exercise Respirometry

The CaloWheel is a motorized running wheel designed for rats or mice, optimized for metabolic measurements during physical activity, known as exercise calorimetry. Enclosed within a transparent, airtight housing, the wheel seamlessly integrates with our fully automated indirect gas calorimetry system, CaloSys, operated via PhenoMaster software. Calorimetric parameters such as oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory exchange ratio (RER), and energy expenditure (EE) are precisely determined at predefined intervals while the test animal follows a customized activity profile set by the experimenter.

Unique Innovation- Weightlifting Module

Our new module is designed to revolutionize resistance training for animals and eliminate the need for invasive or stressful methods. It encourages animals, including reluctant obese individuals, to perform hindleg extensions. For example, to reach a food hopper hidden beneath a hinge with adjustable resistance (% body weight). Researchers can study effects on cellular, biochemical, transcriptional, and metabolic adaptations over short or long terms.

Publications

In Het Panhuis W, Kooijman S, Brouwers B, Verhoeven A, Pronk ACM, Streefland TCM, Giera M, Schrauwen P, Rensen PCN, Schönke M. Obesity 2020; Suppl 1: S93-S103.

Masschelein E, D’Hulst G, Zvick J, Hinte L, Soro-Arnaiz I, Gorski T, von Meyenn F, Bar-Nur O, De Bock K. Skelet Muscle 2020; 10(1): 21.

Wakhloo D, Scharkowski F, Curto Y, Javed Butt U, Bansal V, Steixner-Kumar AA, Wüstefeld L, Rajput A, Arinrad S, Zillmann MR, Seelbach A, Hassouna I, Schneider K, Qadir Ibrahim A, Werner HB, Martens H, Miskowiak K, Wojcik SM, Bonn S, Nacher J, Nave KA, Ehrenreich H. Nat Commun 2020; 11(1):1313.

Wupper S, Fischer A, Luersen K, Ipharraguerre IR, Chikamoto K, Furune T, Ishida Y, Terao K, Rimbach G. J Physiol Pharmacol 2020; 71(3). Epub 2020 Sep 26.

D’Hulst G, Palmer AS, Masschelein E, Bar-Nur O, De Bock K. Front Physiol 2019; 10: 1271.

Mandillo S, Heise I, Garbugino L, Tocchini-Valentini GP, Giuliani A, Wells S, Nolan PM. Dis Model Mech 2014; 7(3): 397-407.